We have long struggled to determine how the first living organisms on Earth came together. Now, surprising evidence hints ...

Researchers from CIIMAR and the University of Helsinki have discovered a new biochemical modification in natural ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

Current demand for plastics and chemical raw materials is met through large-scale production of ethylene from fossil fuels. This makes it necessary to search for new, renewable processes. Using ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. There are three major challenges facing marketed drugs: drug ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The translocation of DNA in polymerase (Pol) enzymes is a critical step for ...

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells hijack various cellular functions to find and exploit energy and other ...

Researchers have developed a new method for engineering enzymes more effectively by utilizing an algorithm that considers their evolutionary history. This method enables targeted mutations that ...

Many companies hope to compete with Novo Nordisk’s and Eli Lilly’s fast-selling GLP-1 drugs for diabetes and weight loss. Structure is among them and, like several others, is working on developing a ...

A recent Scripps Research study has identified the detailed structures of PLD3 and PLD4, enzymes critical for nucleic acid degradation and immune regulation. The discovery, enabling the understanding ...