This year, gene-editing technology was customized to fix mutations in a single patient’s genes for the first time.

To the research team working to save him, KJ Muldoon was first known only as Patient Eta. But within months, KJ’s name — and ...

To compete at iGEM, a sort of science Olympics, teens at a Georgia high school set their sights on finding a better way to ...

The CRISPR gene editing technique has had a dramatic influence on biomedical research, and has even been applied to a few ...

At the end of 2023, the FDA approved Casgevy for sickle cell disease, its first approval for a therapeutic that used the genome editing tool clustered regulatory interspaced palindromic repeats ...

Site-specific recombinases enable efficient cutting and pasting of DNA at specific locations in the genome, where each recombinase recognizes one precise DNA sequence. Due to their ...

Scientists have worked tirelessly to develop ever more precise and efficient CRISPR-Cas systems to reach the ultimate goal: safe and effective CRISPR-Cas-based medical treatments. Over the years, ...

Following on from the discovery of programmable DNA-cutting enzymes known as Fanzors, scientists have found that a diverse range of species possess these genetic 'scissors', which presents a massive ...

Owen T. Tuck, a graduate student in Jennifer Doudna’s lab at the University of California. Owen T. Tuck, a graduate student in Jennifer Doudna’s lab at the University of California, Berkeley, thinks ...

“The importance of the work is in providing a proof of principle: that a fascinating bacterial immune system may be utilized as a tool harboring an impressive recording capacity,” said microbiologist ...