A portion of I-65 in Bartholomew County and Jackson County is closed due to a semi carrying explosive material catching fire.

A 73-year-old woman is on the run after reportedly conning several high-profile financial institutions out of nearly $30 ...

More American newborns are not receiving vitamin K shots, according to a study published Monday in the Journal of the ...

Expect the warmest day around central Indiana so far in December. Indiana quarterback Fernando Mendoza has been named a ...

It’s been a cute trivia question. Who is the Indianapolis Colts’ emergency quarterback? That would be Tyler Warren. The ...

A violent weekend in Indianapolis left three people dead after a series of shootings over the span of just 19 hours on ...

People living on the east side of Indianapolis say they’re fed up after watching a mountain of trash grow just feet from ...

Is Philip Rivers the short-term cure for what’s ailing the Indianapolis Colts? The last quarterback to lead the franchise to ...

The Marion High School Principal has been placed on administrative leave. Marion Community Schools confirmed in a statement ...

INDIANAPOLIS — Indiana State Police are asking for the public’s help in finding a missing 13-year-old girl who disappeared ...

The Indianapolis Colts are planning to bring in 44-year-old quarterback Philip Rivers for a workout on Tuesday.

An investigation is underway after two people were killed in a crash on US 231 in Montgomery County on Monday afternoon.